Theoretical and Practical Approach for Transdermal Drug Delivery using Microneedle for Successful Skin Penetration
Jeevan J.Mahakud, Ziaur Reheman
Department of electronics and Communication engineering, Institute of technical education and research, Bhubaneswar, Odisha, India
Department of electronics and instrumentation engineering, Institute of technical education and research, Bhubaneswar, Odisha, India
With the advent of MEMS, transdermal drug delivery has been developed to increase skin permeability for drug transport. Various microneedle structures have been analyzed theoretically as well as through simulation using COMSOL Multiphysics®. Then computational fluid dynamics has been presented in order to study the behavior of the fluid flow inside the microneedle cavity. In this report, the ...
G. Ruocco, M. V. De Bonis
Engineering College, University of Basilicata, Potenza, Italy
Institute of Food Science and Production, National Research Council, Bari, Italy
Localized convection heat and mass transfer can be intensified and optimized by providing exposure to electromagnetic energy. Conjugate heat and mass transfer are configured by solving the momentum, heat and mass transfer simultaneously in both solid (substrate, comprising of a two-phase chemical species) and fluid (auxiliary air) phases. In this way the heat and mass fluxes vary seamlessly ...
F. Maier, P. Oberdorfer, I. Kocabas, I. Ghergut, M. Sauter
Dpt. Applied Geology, Center of Geosciences, Georg-August-University, Göttingen, Germany
Petroleum and Natural Gas Engineering Department Batman, Batman University, Batman, Turkey
We compare the output of 2D single fracture models as well as analytical solutions of the problem. The temperature signal is evaluated with the heat transfer mode while the flow field is assumed to exhibit Darcy flow everywhere. The problem is time-dependent so we have to take into account a change in the boundary conditions from a Dirichlet to a Neumann condition which is activated at the time ...
School of Mechanical Engineering, University of Birmingham, Birmingham, United Kingdom
A device for monitoring the oxygen consumption of cells has been developed, which consists of two parts; a cell culturing platform (CCP) and an oxygen sensing chip. The CCP possesses inlet and outlet pipes to direct the fluid under the test to the cell culturing chamber through the inlet pipe and goes out of the outlet pipe after being partially consumed by the cells. In this abstract, the ...
Time Dependent Simulations of Thermoelectric Thin Films and Nanowires for Direct Determination of their Efficiency with COMSOL Multiphysics®
M. Muñoz Rojo, J. Jose Romero, D. Ramos, D. Borca-Tasciuc, T. Borca-Tasciuc, M. Martín Gonzalez
Instituto de Microelectrónica de Madrid, Madrid, Spain
Rensselaer Polytechnique Institute, Troy, New York, USA
Thermoelectric materials are one of the most promising materials for future and nowadays energy harvesting devices, as they can convert heat into electricity and vice-versa. The efficiency of thermoelectric materials is related with the figure of merit, ZT. Our work deals with the determination of the parameters that affect the measurement of the ZT with the Harman technique and the best ...
E. Holzbecher, S. Oehlmann
Georg-August Universität Göttingen, Göttingen, Germany
Phenomena of heat and mass transfer are often compared, in various porous media applications. Questions of practical interest are, for example, if tracers can be used for the prediction of heat flow, or vice versa if heat can be utilized as, possibly retarded, tracer for predicting the migration of contaminants, nutrients or other substances. Using numerical modelling in artificial porous media ...
Computational Study on Transition of Oil-Water Flow Morphology due to Sudden Contraction in Microfluidic Channel - new
J. Chaudhuri, S. Timung, T. K. Mandal, D. Bandyopadhyay
Indian Institute of Technology Guwahati, Guwahati, Assam, India
The flow morphology of two immiscible fluids in a microfluidic device finds numerous applications such as emulsification, synthesis of nanomaterials , lab-on-a-chip devices and biological analysis . It offers many advantages over the conventional macroscopic devices because of its availability for higher surface to volume ratio, ability to handle small volume of fluids, easier process ...
Á. Sainz [1,2], A. Nardi , E. Abarca , F. Grandía 
 Amphos 21 Consulting S.L., Barcelona, Spain
 Université Toulouse III - Paul Sabatier, Toulouse, France
Nowadays, gas and nuclear waste storage, shale gas and EOR exploitation rise the need to understand and predict the fate of multiphase flows in the underground. Various formulations for multiphase flow arise from different linear combinations of governing equations and choice of associated unknowns. Each formulation has its own benefits and drawbacks; and the optimal may vary depending on the ...
Numerical Study and Simulation in COMSOL Multiphysics of the Dilution Process during Dust Sampling in Dry Machining
B. Wenga-Ntcheping, A. Djebara, R. Kamguem, J. Kouam, V. Songmene
University of Quebec-École de Technologie Supérieure, Montreal, Canada
Dilution’s issue during dry machining have raised the interest’s environmental researchers and engineers. In fact, the sampling of dust emitted during dry machining was a serious problem for air quality evaluation at the workplace. Furthermore, the best sampling of fine and ultrafine particles produced during material cutting, passed through the dilution of high particle concentration (number, ...
L. Nespoli, M. Bianchi Janetti, F. Ochs
Politecnico di Milano, Milan, Italy
University of Innsbruck, Innsbruck, Austria
A model for the conjugate simulation of heat and moisture transfer inside porous materials and fluid domains is implemented in COMSOL Multiphysics®. The results of this model are compared with those obtained through a simplified approach: the line-source approach. The models are both validated with experimental data and with numerical results from other authors. On the one hand the conjugate ...