Study of Fluid and Mass Adsorption Model in the QCM-D Sensor for Characterization of Biomolecular Interaction
H.J. Kwon, C.K. Bradfield, B.T. Dodge, and G.S. Agoki
Department of Engineering and Computer Science, Andrews University, Berrien Springs, Michigan, USA
Increasing attention has been paid to application of the quartz crystal microbalance with dissipation (QCM-D) sensor for monitoring biomolecular interactions. This paper focuses on a practical application of protein-protein binding affinity measurement at low concentrations and minimal sample sizes (50-200 μl of 20-200 nM), which results in low signal measurement. A model simulating fluid ...
Robust and Reliability-based Design Optimization of Electromagnetic Actuators Using Heterogeneous Modeling with COMSOL Multiphysics and Dynamic Network Models
H. Neubert, A. Kamusella, and T-Q. Pham
Technische Universität Dresden, Germany
OptiY e. K. Aschaffenburg, Germany
For an exemplary electromagnetic actuator used to drive a Braille printer, a design optimization was performed. The optimization involves stochastic variables and comprises nominal optimization, robustness analysis and robust design optimization. A heterogeneous model simulates the static and the dynamic behavior of the actuator and its non-linear load. It consists of a network model in ...
A. Regtmeier, A. Weddemann, I. Ennen, and A. Hütten
Dept. of Physics, Thin Films and Physics of Nanostructures, Bielefeld University, Bielefeld, Germany
Dept. of Elect. Eng. and Comp. Science, Lab. for Electromagnetic and Electronic Syst., MIT, Cambridge, MA
Institute of Solid State Physics, Vienna University of Technology, Vienna, Austria
Superparamagnetic nanoparticles have a wide range of applications in modern electric devices. Recent developments have identified them as components for a new type of magnetoresistance sensor. We propose a model for the numeric evaluation of the sensor properties. Based on the solutions of the Landau-Lifshitz-Gilbert equation for a set of homogeneously magnetized spheres arranged in highly ...
G. S. Masi, S. V. De Guido, G. Montagna, C. Martucci, P. M. Congedo, L. Vasanelli , M. G. Manera, R. Rella
Department of Innovation Engineering, University of Salento, Lecce, Italy
CNR-IMM, Lecce, Italy
Introduction: Accurate fluid temperature control in microfluidic channels is a requirement for many lab-on-chip and micro-reactors.Thin films resistive metal heaters have proven to be the best choice for localizing heating applications with integrated microfluidic systems. A thin platinum layer has been chosen as the metal used to realize the meander because of its positive and linear ...
N. Das, C. R. Chaudhuri
Department of Electronics and Telecommunication, BESUS, Howrah, West Bengal, India
In this paper, we have proposed an impedance biosensor based on polymer nanowire (made of polyaniline) for efficient electric field mediated capture of biomolecules. Existing polymer nanowire based biosensors fail to achieve high sensitivity for low surface to volume ratio as the whole length of the nanowire is exposed to the analyte .Also biosensors are dependent on diffusion mediated capture ...
V. Tiwari, R. Sharma, G. Srivastava, R. Dwivedi
Jaypee Institute of Information Technology, Noida, Uttar Pradesh, India
Cantilever beam-type transducers have been in great demand and explored widely in the recent years, typically in thin film form because of their sensor and actuator applications. The piezoelectric cantilever is the most preferred structure employed in technological applications. Depending on the required flexural motion and sensitivities, these piezoelectric cantilevers can be used in unimorph, ...
A. G. S. Barreto Neto , A. M. N. Lima , C. S. Moreira ,
 Instituto Federal de Ciência e Tecnologia - IFPB, João Pessoa, PB, Brasil
 Universidade Federal de Campina Grande - UFCG, Campina Grande, PB, Brasil
Este trabalho trata do dimensionamento da estrutura bocal/difusor utilizando a simulação computacional com fronteira móvel. Esse tipo de simulação contempla toda estrutura da bomba, isto é, câmara de bombeamento, difusor e área de dispersão de fluxo, de modo a contabilizar o refluxo em função da estrutura, possibilitando um projeto mais realísticos da estrutura.
D. Kappe, A. Hütten
University of Bielefeld, Bielefeld, Germany
The possibility to detect and probe molecules in microfluidic devices gives rise to interesting applications. There are different approaches how to detect and probe particles, but a common step, for most methods, is to place the particles on a sensor. This can be done by applying external field gradients, or in this case by utilizing gravitational and hydrodynamic effects. Therefore, the sensor ...
A. Ivanov, U. Mescheder
Furtwangen University, Furtwangen, Germany
In the presented work the dynamic simulation of a silicon anodization process is performed. Two mechanisms of etch form development (diffusion in electrolyte, current flow) are considered and simulated. Influence of electrolyte conductivity and radius of the opening in the masking layer is discussed.
National Nano Device Laboratories (NDL), National Applied Research Laboratories, Taipei, Taiwan
Some types of rare pathogens can be detected and identified in human blood through a low-cost and label-free method. The On-Chip SESR identification process has a fast detection time (about 5 minutes) and a low detection limit. Discrimination of a species is done by sorting red blood cells from bacteria. Simulations of dielectrophoretic (DEP) force, dual layer electrodes, and dynamic separation ...