Numerical Prediction of Particle Dynamics Within a Cytometer. Application to Counting and Sizing by Impendance Measurement
HORIBA Medical, Montpellier, France
This paper describes how to numerically tackle the problem of counting and sizing particles by impedance measurement in an orifice–electrode system. The model simulate the particle dynamics submitted to strong hydrodynamic stresses through a microorifice and compute the voltage pulses generated by the modification of the inner dielectric medium. This FSI problem is solved on a moving mesh by ...
D. Iber, J. Vollmer, D. Menshykau
Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland
Most models of biological pattern formation are simulated on continuous domains even though cells are discrete objects that provide internal boundaries to the diffusion of regulatory components. In our previous papers on simulating organogenesis in COMSOL Multiphysics® (Germann et al COMSOL Multiphysics® Conf Procedings 2011; Menshykau and Iber, COMSOL Multiphysics® Conf Proceedings 2012) we ...
An Assessment of the Suitability of the Body and Adult Head Coils for Transmission during Paediatric Magnetic Resonance Imaging
G.R. Cook, M.J. Graves, F.J. Robb, D.J. Lomas
Department of Radiology, University of Cambridge, Cambridge, United Kingdom
General Electric Healthcare Coils, Aurora, Ohio, USA
MRI offers many advantages over other modalities and its lack of ionizing radiation is important for children, but can be limited by the radio-frequency (RF) coils available. This work calculates Specific Absorption Rate (SAR) and homogeneity of the RF transmit field (B1+) when imaging infants in adult coils. Two birdcage-type coils were loaded by a tissue model and their B1+ homogeneities ...
O. Henao, V. Gómez, I. De la Pava, J. Sánchez
Grupo Fisiología Celular y Aplicada, Universidad Tecnológica de Pereira, Pereira, Risaralda, Colombia
Electroporation is an increase of the cell membrane permeability due to the formation of aqueous pores in it when the cell is under the influence of an intense electric field . The formation of such pores in the membrane can be used to enhance the uptake of chemotherapeutic drugs into the cell in a cancer treatment known as electrochemotherapy . In some cases the direct experimental ...
P. Guha, P. Sharma, V. Malhotra, S. Mishra
CSIR - Central Scientific Instruments Organisation, Chandigarh, India
Proper storage of grains depends on minimizing attacks of insects, fungi, mites, etc. Development of such pests can be controlled by controlling the temperature of the storage chamber. Hence, before designing grain storage chambers, mathematical modeling and numerical simulations should be performed to predict the temperature distributions. Changes in storage temperature may occur due to several ...
Hemodynamic Therapy of Middle Cerebral Artery Vasospasm Guided by a Multiphase Model of Oxygen Transport
S. Conrad[1,2], P. Chittiboina, and B. Guthikonda
Department of Bioinformatics and Computational Biology, Louisiana State University Health Sciences Center, Shreveport, LA, USA
Department of Biomedical Engineering, Louisiana Tech University, Ruston, LA, USA
Department of Neurosurgery, Louisiana State University Health Sciences Center, Shreveport, LA, USA
Cerebral vasospasm is a complication of subarachnoid hemorrhage and other neurosurgical emergencies that reduce blood flow to the brain. Part of the approach to management of vasospasm is to improve flow through the stenotic areas by reducing by decreasing blood viscosity and enhancing flow through the stenosis. To examine the interaction of these factors, we applied computational fluid dynamics ...
A. Jeremic, and A. Atalla
McMaster University, Hamilton, ON, Canada
In this paper, we develop a mathematical model to simulate the movement of bacteria into and within a capillary segment. Also, we model the transportation through capillary walls by means of anisotropic diffusivity that depends on the pressure difference across the capillary walls. By solving the model using COMSOL, it was possible to predict the concentration of bacteria at points within the ...
L. Murtomäki, and S. Kotha
University of Helsinki, Centre for Drug Research, Helsinki, Finland
Drug therapy of the posterior part of an eye is very challenging. Yet, in USA alone, there are almost 2 million people affected by age related macular degeneration. When designing a strategy for controlled-release drug delivery, it is important to take into account of physiology, absorption, distribution, metabolism, and excretion properties of a drug. Therefore, the aims of this study are: 1) to ...
The Effect of Cartilaginous Rings on Deposition by Convection, Brownian Diffusion and Electrostatics
Luleå University of Technology, Luleå, Sweden
This paper presents a numerical study of the deposition of spherical charged nanoparticles caused by convection and Brownian diffusion in a pipe with a cartilaginous ring structure. The model is supposed to describe deposition of charged particles in the upper generations of the tracheobronchial tree of the human lung. The upper airways are characterized by a certain wall structure called ...
B. Liu, T. C. Zhu
Department of Radiation Oncology, School of Medicine, University of Pennsylvania, Philadelphia, PA, USA
Deformable image registration is a form of medical image processing that can provide insights into the development of phenomenon and variation in normal anatomical structure over time. Prior to post-operative pleural photodynamic therapy (PDT), a series of CT scans of lungs will be acquired. During PDT treatment, an infrared navigation system is used to contour the lungs and provide real-time ...