N. Delmonte, F. Giuliani, P. Cova
Dipartimento di Ingegneria dell'Informazione, Università degli Studi di Parma, Parma, Italy
Introduction: Power electronic converters such as those for High Energy Physics Experiments (HEPEs) must operate in thermally hostile environment. Heat generated by electronics components must be conveniently dissipated to ensure electrical performances and improve reliability. Due to the high power density, the presence of closed environments, and the requirement of non-thermal interaction with ...
Lawrence Berkeley National Laboratory, Hayward, CA, USA
A pocket-size portable particle size detector for diesel and cigarette smoke aerosols is being designed using particle size and composition methods. Aerodynamics, fluid properties, material composition and aerosol composition are taken into account. Testing methods for the design include using an impactor and virtual impactor with two quartz crystal resonators to determine particle composition ...
J. Martel, N. Elabbasi, D. Quinn, J. Bergstrom, M. Toner
BioMEMS Resource Center, Massachusetts General Hospital, Boston, MA, USA
Veryst Engineering, Needham, MA, USA
Inertial focusing is a promising microfluidic technique for separating and concentrating cells of interest, processes routinely utilized in many medical procedures. This phenomenon is characterized by suspended particles in a flow spontaneously migrating across streamlines to equilibrium positions within a channel cross-section. We developed CFD models in COMSOL Multiphysics® to predict the ...
M. Weterings, M. Beyrer
Institute of Life Sciences HesSo Valais, Sion, Valais, Switzerland
Partial differential equations (PDEs) in multiple dimensions may often be solved in a lower dimension if the problem domain contains a symmetry (cylindrical, spherical, translational, etcetera). For problems involving PDEs with helical symmetry we propose a method, with both low computational costs and low complexity, that reduces the domain to a 2D axial plane while retaining 3D Cartesian ...
J.M. Gozalvez-Zafrilla, M.C. Leon-Hidalgo, J. Lora-Garcia, A. Santafe-Moros, and J.C. Garcia-Diaz
Universidad Politecnica de Valencia, Valencia, Spain
Brine disposal from desalination plants placed in inland areas far from sea is an important problem. Evaporation ponds can be used for reducing the waste to solid state but they require huge amounts of land. Evaporation using arrays of wet surfaces can minimize the land requirements. One characteristic of the methods based on natural evaporation is the uncertainty associated to the influent ...
Computationally Assisted Design and Experimental Validation of a Novel ‘Flow-Focussed’ Microfluidics Chip for Generating Monodisperse Microbubbles
M. Conneely, V. Hegde, H. Rolfsnes, A. Mason, D. McLean, C. Main, F.J.D. Smith, W.H.I. McLean, P.A. Campbell
Carnegie Physics Laboratory, University of Dundee, Dundee, Scotland, United Kingdom
Division of Molecular Medicine, University of Dundee, Dundee, Scotland, United Kingdom
Whilst initially developed as a diagnostic aid to improve echogenicity in ultrasound imaging, gas-filled lipid microbubbles are now emerging as a next generation \'theranostic\' tool in the medical arena. Here, their therapeutic potential has now been realized through their unique capability to deliver molecular species such as drugs and genes by means of disrupting the cell membrane in response ...
R. Sikorski, B. Chapman, T. Merrill
Rowan University, Glassboro, NJ, USA
A CFD cardiac catheter model was developed to determine the potential for blood hemolysis during administration of local therapeutic hypothermia using a CoolGuide catheter. In vivo animal studies have shown that mild hypothermia may reduce reperfusion injury often associated with heart attack. The CoolGuide Catheter System (CCS) delivers rapid local cooling through a cardiac catheter, reducing ...
F. Mansilla, L. Voisin 
Advanced Mining Technology Center, Chile University, Santiago, Chile
Department of Mining Engineering, Advanced Mining Technology Center, Chile University, Santiago, Chile
Throughout history, the copper pyrometallurgical processes have been carried out mostly in discontinuous or batch systems. In recent decades new continuous technologies have been developed but focused only on Smelting and Converting stages leaving aside the Refining one. In 2002 a novel technology was proposed by the Department of Mining Engineering of Chile University which consists in two ...
Ritsumeikan University, Shiga, Japan
The vertical axis wind turbine design depicted in (Fig.1) is widely considered a wind turbine of a wind power generation system because it can be easily miniaturized, it generates low noise, and it rotates regardless of wind direction. The vertical axis wind turbine has, however, low rotation performance when compared with that of a horizontal axis wind turbine. Therefore, we need to improve the ...
Development of a Multiphase, Multispecies Droplet Evaporation Model for Optimization of Desiccation Preservation Techniques
A. Sinkevich, S. Bhowmick , M. Raessi
University of Massachusetts Dartmouth, North Dartmouth, MA, USA
Biopreservation deals with the protection and storage of complex biologics such as proteins, lipids, and recently, mammalian cells. One preservation method, known as lyopreservation, involves placing a biologic inside a water droplet with some type of sugar excipient (sucrose, trehalose, etc.) and drying the solution convectively. We are currently developing a model that couples the two-phase ...