Theoretical and Practical Approach for Transdermal Drug Delivery using Microneedle for Successful Skin Penetration
Jeevan J.Mahakud, Ziaur Reheman
Department of electronics and Communication engineering, Institute of technical education and research, Bhubaneswar, Odisha, India
Department of electronics and instrumentation engineering, Institute of technical education and research, Bhubaneswar, Odisha, India
With the advent of MEMS, transdermal drug delivery has been developed to increase skin permeability for drug transport. Various microneedle structures have been analyzed theoretically as well as through simulation using COMSOL Multiphysics®. Then computational fluid dynamics has been presented in order to study the behavior of the fluid flow inside the microneedle cavity. In this report, the ...
Numerical Modeling and Performance Optimization Study of a Dehumidification Process in Nuclear Waste Storage
Sogin Spa, Rome, Italy
One of the main parameters to consider during the nuclear waste storage design phase is the drum corrosion risk. The humid-air corrosion models available in literature predict that, for carbon steel, the phenomena start to become appreciable for relative humidity (RH) values close to 65%. In general, the corrosion rate increases exponentially with relative humidity above the RH threshold. To ...
Modeling of Wettability Alteration during Spontaneous Imbibition of Mutually Soluble Solvents in Mixed Wet Fractured Reservoirs - new
M. Chahardowli, H. Bruining
Delft University of Technology, Delft, The Netherlands
Mutually-soluble solvents can enhance oil recovery both in completely and partially water wet fractured reservoirs. When a strongly or partially water-wet matrix is surrounded by an immiscible wetting phase in the fracture, spontaneous imbibition is the most important production mechanism. Initially, the solvent moves with the imbibing brine into the core. However, upon contact with oil, as the ...
Using Computational Fluid-Dynamics (CFD) for the Evaluation of Tomato Puree Pasteurization: Effect of Orientation of Bottle - new
A. R. Lespinard[1, 2], R. H. Mascheroni[1, 2]
Centro de Investigación y Desarrollo en Criotecnología de Alimentos (CIDCA), La Plata, Buenos Aires, Argentina
Universidad Nacional de La Plata (UNLP), La Plata, Buenos Aires, Argentina
Determination of the temperature in liquid foods may be derived by measurements or by modeling. However, the placement of thermocouple probes to record temperature in the container disturbs the flow patterns. For this purpose, Computational fluid-dynamics (CFD) offers a powerful tool for predictions of the transient temperature and velocity profiles during natural convection heating of liquid ...
B. Srinivasan, J. Hickman, M. Shuler
University of Central Florida, Orlando, FL, USA
Cornell University, Ithaca, NY, USA
A micropump delivers fluid between different components of a microfluidic device in a controlled manner. The elimination of micropump can reduce the design complexity, simplify fabrication, shrink the device footprint and decrease the set-up time required for the operation of the microfluidic device. One such pumpless microfluidic device for body-on-a-chip application for drug toxicity studies ...
R. P. Ruby, G. Kulkarni, U. Kanade
Noumenon Multiphysics Pvt. Ltd., Pune, Maharashtra, India
Oneirix Engineering Laboratories Pvt. Ltd., Pune, Maharashtra, India
Seals or gaskets that are compressed between walls of a container are important to many industrial applications. Understanding the performance of such seals requires an understanding of the microscopic geometry of the sealing surfaces, because the fluid seeps around the undulations of such surfaces. This paper presents strong computational evidence that the microgeometry of such surfaces depends ...
Civil and Environmental Engineering, Stanford University, Stanford, CA, USA
In many groundwater studies, the areal extent of an aquifer is much larger than its thickness so that flow and transport take place primarily in horizontal directions. Thus, the most common type of modeling in practical applications is two-dimensional involving vertically averaged dependent variables, primarily hydraulic head and solute concentration. This is a tutorial on depth-averaged ...
Ritsumeikan University, Kusatsu City, Shiga, Japan
There are two types of vertical axis wind turbine, drag-type and lift-type. Drag type wind turbine can rotate in low speed wind condition, although its rotation speed is low. Lift type wind turbine can rotate at higher speed, although it works only in high speed wind condition. This study investigates new blade profile that realize rotation in low wind speed condition and higher rotation speed by ...
Research Center for Power Engineering Problems of the Russian Academy of Sciences, Kazan, Russia
The influences of curvature effects and swirl intensities for Non-Newtonian viscous fluid flow in a curved tube have been numerically investigated by using COMSOL Multiphysics®. The twisted tape, which are located directly in front of the curved part, are used as swirl flow generators. The tape is twisted until it reaches an angle of 90 degrees and turns right. Swirling flow, getting into the ...
Thermal Study of Valve Regulated Lead Acid Batteries and Electronics Chamber Used in Stand-Alone Street Lighting Applications - new
D. Groulx, J. Skaalum, T. Jamieson
Mechanical Engineering, Dalhousie University, Halifax, NS, Canada
This paper presents a study on the heat generation of Valve-Regulated Lead Acid (VRLA) batteries used in off-grid streetlighting applications from PoleCo, a Halifax based company. One goal of the project was to produce validated COMSOL® models of the enclosure that holds these VRLA batteries. This model can then be used to investigate methods of reducing the temperature of the batteries based on ...